The IUPAC published in 1973 as a comprehensive definition: ‘Medicinal chemistry concerns the discovery, the development, the identification and the interpretation of the mode of action of biologically active compounds at the molecular level. Emphasis is put on the discovery and development of drug, as indicated by the adjective ‘medicinal.’ However, as the definition indicates, the interests of Medicinal Chemistry are not restricted to drugs but also imply bio-active compounds in general.’ Medicinal chemistry is the study of how novel drugs can be designed and developed. Rationale for studying Medicinal Chemistry: Students who are keen to involve them in the research, synthesis of new drug molecules and wishing to know the overall drug mechanism will need to have complete knowledge of medicinal chemistry. Also, in order to engage in the industrial pharmacy, pharmacy graduates have to become thoroughly knowledgeable about the design and discovery of new compounds that is suitable for use as drugs.